2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-103638R
    3-Methoxytyramine (hydrochloride) (Standard)
    3-Methoxytyramine (hydrochloride) (Standard) is the analytical standard of 3-Methoxytyramine (hydrochloride). This product is intended for research and analytical applications. 3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1).
    3-Methoxytyramine (hydrochloride) (Standard)
  • HY-W707158
    Norfenfluramine hydrochloride
    Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, formed through N-dealkylation of Fenfluramine. Norfenfluramine hydrochloride is also a potent anorexiant. Norfenfluramine hydrochloride can regulate serotonergic neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects after acute administration.
    Norfenfluramine hydrochloride
  • HY-129708
    LU 2443
    LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h.
    LU 2443
  • HY-126833B
    Myristoyl coenzyme A triammonium
    Myristoyl coenzyme A triammonium (14:0 Coenzyme A) is a type of long-chain acyl-CoA, which is the activated form of long-chain fatty acids and serves as a crucial lipid metabolite.
    Myristoyl coenzyme A triammonium
  • HY-141410
    Fluticasone dimer impurity
    Fluticasone dimer impurity is a dimeric impurity of Fluticasone Propionate. Fluticasone propionate is a corticosteroid with comparatively high receptor affinity and topical activity.
    Fluticasone dimer impurity
  • HY-170629
    3,4-Dimethylmethcathinone metabolite hydrochloride
    3,4-Dimethylmethcathinone metabolite hydrochloride is a metabolite of 3,4-Dimethylmethcathinone. 3,4-Dimethylmethcathinone is a stimulant agent.
    3,4-Dimethylmethcathinone metabolite hydrochloride
  • HY-168367
    2-Hydroxyethylflurazepam
    2-Hydroxyethylflurazepam (compound II) is a metabolite of Flurazepam.
    2-Hydroxyethylflurazepam
  • HY-W012982R
    3-Amino-2-oxazolidinone (Standard)
    3-Amino-2-oxazolidinone (Standard) is the analytical standard of 3-Amino-2-oxazolidinone. This product is intended for research and analytical applications. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo.
    3-Amino-2-oxazolidinone (Standard)
  • HY-W653919
    SN-38 glucuronide-d3
    SN-38 glucuronide-d3 is deuterium labeled SN-38 glucuronide. SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer.
    SN-38 glucuronide-d<sub>3</sub>
  • HY-130318
    Quinidine N-oxide
    Quinidine N-oxide is a pharmacologically inactive metabolite of Quinidine (HY-B1751H). Quinidine is an active probe of CYP3A4.
    Quinidine N-oxide
  • HY-121745R
    Phosmet oxon (Standard)
    Phosmet oxon (Standard) is the analytical standard of Phosmet oxon. This product is intended for research and analytical applications. Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits.
    Phosmet oxon (Standard)
  • HY-W016388R
    9-Fluorenol (Standard)
    9-Fluorenol (Standard) is the analytical standard of 9-Fluorenol. This product is intended for research and analytical applications. 9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 μM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo.
    9-Fluorenol (Standard)
  • HY-Z8537
    Desmethyl mirtazapine hydrochloride
    Desmethyl mirtazapine (Normirtazapine) hydrochloride is a metabolite of Mirtazapine (HY-B0352). Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent.
    Desmethyl mirtazapine hydrochloride
  • HY-133010R
    Tamoxifen N-oxide (Standard)
    Cyclanilide (Standard) is the analytical standard of Cyclanilide. This product is intended for research and analytical applications. Cyclanilide (RPA90946) serves as a plant growth regulator that is applied to cotton during various growth stages.
    Tamoxifen N-oxide (Standard)
  • HY-A0255
    Clocortolone
    Clocortolone is a synthetic glucocorticoid steroid and corticosteroid ester. Clocortolone can be used for seborrheic dermatitis, contact dermatitis, atopic dermatitis, and psoriasis. Clocortolone has local in vivo potency and is not easily absorbed into systemic circulation.
    Clocortolone
  • HY-W016033
    Pantoprazole sulfide
    Pantoprazole sulfide is a metabolite of Pantoprazole (HY-17507), which is a proton-pump inhibitor.
    Pantoprazole sulfide
  • HY-100657R
    meta-Fexofenadine (Standard)
    meta-Fexofenadine (Standard) is the analytical standard of meta-Fexofenadine. This product is intended for research and analytical applications. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial.
    meta-Fexofenadine (Standard)
  • HY-W014993R
    1,3-Dimethyluric acid (Standard)
    1,3-Dimethyluric acid (Standard) is the analytical standard of 1,3-Dimethyluric acid. This product is intended for research and analytical applications. 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
    1,3-Dimethyluric acid (Standard)
  • HY-130239S
    14(S)-HDHA-d5
    14(S)-HDHA-d5 (14(S)-HDoHE-d5) is deuterium labeled 14(S)-HDHA. 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway.
    14(S)-HDHA-d<sub>5</sub>
  • HY-W704749
    7-Hydroxychlorpromazine hydrochloride
    7-Hydroxychlorpromazine hydrochloride is the active metabolite of Chlorpromazine (HY-12708). 7-Hydroxychlorpromazine hydrochloride can increase prolactin levels in rats. 7-Hydroxychlorpromazine hydrochloride can increase dopamine turnover and has a sedative effect. In addition, 7-Hydroxychlorpromazine hydrochloride can effectively inhibit amphetamine-induced stereotyped behavior in rats and is used in the study of psychosis.
    7-Hydroxychlorpromazine hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity